2Q0A
Structure and rearrangements in the carboxy-terminal region of SpIH channels
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | polymer | 200 | 23427.7 | 2 | UniProt (O88703) Pfam (PF00027) | Mus musculus (house mouse) | Brain cyclic nucleotide-gated channel 2, BCNG-2, Hyperpolarization-activated cation channel 1, HAC-1 |
| 2 | C, D (A, B) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 2 | Chemie (PCG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 215 | Chemie (HOH) |
Sequence modifications
A, B: 443 - 640 (UniProt: O88703)
| PDB | External Database | Details |
|---|---|---|
| Gly 441 | - | cloning artifact |
| Ser 442 | - | cloning artifact |
| Asp 636 | Ile 636 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46855.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 690.4 | |
| All* | Total formula weight | 47545.9 |
