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2PZY

Structure of MK2 Complexed with Compound 76

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
MAP kinase-activated protein kinase 2polymer32437521.34UniProt (P49137)
Pfam (PF00069)
Homo sapiens (human)MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MK2
2E, F
(A, B)
(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDEnon-polymer440.52Chemie (B18)
3G
(C)
STAUROSPORINEnon-polymer466.51Chemie (STU)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight150085.3
Non-Polymers*Number of molecules3
Total formula weight1347.6
All*Total formula weight151432.9
*Water molecules are not included.

239803

PDB entries from 2025-08-06

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