2PXH

Crystal structure of a bipyridylalanyl-tRNA synthetase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tyrosyl-tRNA synthetase	polymer	314	36040.7	1	UniProt (Q57834) Pfam (PF00579)	Methanocaldococcus jannaschii	Tyrosine--tRNA ligase, TyrRS
2	B (A)	3-(2,2'-BIPYRIDIN-5-YL)-L-ALANINE	non-polymer		243.3	1	Chemie (BP5)
3	C (A)	water	water		18.0	278	Chemie (HOH)

Sequence modifications

A: 1 - 306 (UniProt: Q57834)

PDB	External Database	Details
Gly 32	Tyr 32	engineered mutation
Tyr 65	Leu 65	engineered mutation
Ala 70	His 70	engineered mutation
Glu 155	Gln 155	engineered mutation
Gly 158	Asp 158	engineered mutation
Trp 159	Ile 159	engineered mutation
Ser 162	Leu 162	engineered mutation
Leu 307	-	expression tag
Glu 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36040.7
Non-Polymers*	Number of molecules	1
	Total formula weight	243.3
All*	Total formula weight	36284.0

*Water molecules are not included.