2PWV
tRNA guanine transglycosylase E235Q mutant in complex with preQ0
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Queuine tRNA-ribosyltransferase | polymer | 386 | 42924.7 | 1 | UniProt (P28720) Pfam (PF01702) In PDB | Zymomonas mobilis | tRNA-guanine transglycosylase, Guanine insertion enzyme |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | 2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE | non-polymer | 175.1 | 1 | Chemie (PQ0) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 1 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Gln 235 | Glu 235 | engineered mutation |
| Lys 312 | Thr 312 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42924.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 793.1 | |
| All* | Total formula weight | 43717.8 |
