2PW3
Structure of the PDE4D-cAMP complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 327 | 37705.7 | 2 | UniProt (Q08499) Pfam (PF00233) In PDB | Homo sapiens (human) | DPDE3, PDE43 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 2 | Chemie (CMP) | |||
| 4 | water | water | 18.0 | 528 | Chemie (HOH) |
Sequence modifications
A, B: 86 - 412 (UniProt: Q08499)
| PDB | External Database | Details |
|---|---|---|
| Asn 201 | Asp 503 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75411.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 789.2 | |
| All* | Total formula weight | 76200.7 |
