2PTQ
Crystal structure of Escherichia coli adenylosuccinate lyase mutant H171N with bound AMP and fumarate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Adenylosuccinate lyase | polymer | 462 | 52412.4 | 2 | UniProt (P0AB89) Pfam (PF00206) Pfam (PF08328) In PDB | Escherichia coli | Adenylosuccinate, ASL |
2 | A, B | FUMARIC ACID | non-polymer | 116.1 | 2 | Chemie (FUM) | |||
3 | A, B | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
4 | water | water | 18.0 | 650 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 456 (UniProt: P0AB89)
PDB | External Database | Details |
---|---|---|
Leu 154 | Ile 154 | conflict |
Asn 171 | His 171 | engineered mutation |
His 457 | - | expression tag |
His 458 | - | expression tag |
His 459 | - | expression tag |
His 460 | - | expression tag |
His 461 | - | expression tag |
His 462 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 104824.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 926.6 | |
All* | Total formula weight | 105751.5 |