2PSV
Crystal Structure of wild type HIV-1 protease in complex with CARB-KB45
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10815.8 | 2 | UniProt (O38732) Pfam (PF00077) UniProt (by SIFTS) (O38707) | Human immunodeficiency virus 1 | |
| 2 | C, F, G (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | E (A) | N-{(1S,2R)-1-BENZYL-3-[(CYCLOPROPYLMETHYL)(2-FURYLSULFONYL)AMINO]-2-HYDROXYPROPYL}-N'-METHYLSUCCINAMIDE | non-polymer | 477.6 | 1 | Chemie (MUV) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: O38732)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21631.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 821.5 | |
| All* | Total formula weight | 22453.1 |
