2PSQ
Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fibroblast growth factor receptor 2 | polymer | 370 | 42138.3 | 2 | UniProt (P21802) Pfam (PF07714) | Homo sapiens (human) | FGFR-2, Keratinocyte growth factor receptor 2, CD332 antigen |
| 2 | C, D, E, F (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 188 | Chemie (HOH) |
Sequence modifications
A, B: 413 - 768 (UniProt: P21802)
| PDB | External Database | Details |
|---|---|---|
| Met 399 | - | expression tag |
| Gly 400 | - | expression tag |
| Ser 401 | - | expression tag |
| Ser 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
| His 406 | - | expression tag |
| His 407 | - | expression tag |
| His 408 | - | expression tag |
| Ser 409 | - | expression tag |
| Gln 410 | - | expression tag |
| Asp 411 | - | expression tag |
| Pro 412 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84276.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 84660.9 |
