2PSQ

Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Fibroblast growth factor receptor 2	polymer	370	42138.3	2	UniProt (P21802) Pfam (PF07714) In PDB	Homo sapiens (human)	FGFR-2, Keratinocyte growth factor receptor 2, CD332 antigen
2	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3		water	water		18.0	188	Chemie (HOH)

Sequence modifications

A, B: 413 - 768 (UniProt: P21802)

PDB	External Database	Details
Met 399	-	expression tag
Gly 400	-	expression tag
Ser 401	-	expression tag
Ser 402	-	expression tag
His 403	-	expression tag
His 404	-	expression tag
His 405	-	expression tag
His 406	-	expression tag
His 407	-	expression tag
His 408	-	expression tag
Ser 409	-	expression tag
Gln 410	-	expression tag
Asp 411	-	expression tag
Pro 412	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84276.7
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	84660.9

*Water molecules are not included.