2PRM
The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydroorotate dehydrogenase, mitochondrial | polymer | 367 | 39856.5 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (human) | Dihydroorotate oxidase; DHOdehase |
| 2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
| 3 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
| 4 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39856.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 612.4 | |
| All* | Total formula weight | 40469.0 |
