2PMI

Structure of the Pho85-Pho80 CDK-cyclin Complex of the Phosphate-responsive Signal Transduction Pathway with Bound ATP-gamma-S

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Cyclin-dependent protein kinase PHO85	polymer	317	36356.7	2	UniProt (P17157) Pfam (PF00069)	Saccharomyces cerevisiae (baker's yeast)	Serine/threonine-protein kinase PHO85; Negative regulator of the PHO system
2	B, D (B, D)	PHO85 cyclin PHO80	polymer	293	33273.8	2	UniProt (P20052) Pfam (PF08613)	Saccharomyces cerevisiae (baker's yeast)	Phosphate system cyclin PHO80; Aminoglycoside antibiotic sensitivity protein 3
3	E (A)	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER	non-polymer		523.2	1	Chemie (AGS)
4	F, G (B, D)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)

Sequence modifications

A, C: 1 - 305 (UniProt: P17157)

PDB	External Database	Details
Met 306	-	expression tag
Gly 307	-	expression tag
Gly 308	-	expression tag
Ser 309	-	expression tag
Arg 310	-	expression tag
Ser 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	139260.9
Non-Polymers*	Number of molecules	3
	Total formula weight	913.7
All*	Total formula weight	140174.6

*Water molecules are not included.