2PIN
Thyroid receptor beta in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Thyroid hormone receptor beta-1 | polymer | 253 | 28624.2 | 2 | UniProt (P10828) Pfam (PF00104) | Homo sapiens (human) | |
| 2 | C, F (A, B) | [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID | non-polymer | 621.9 | 2 | Chemie (4HY) | |||
| 3 | D, G (A, B) | 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE | non-polymer | 216.3 | 2 | Chemie (LEG) | |||
| 4 | E (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
A, B: 209 - 461 (UniProt: P10828)
| PDB | External Database | Details |
|---|---|---|
| Arg 355 | Asp 355 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57248.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1772.6 | |
| All* | Total formula weight | 59020.9 |
