2PID

Crystal structure of human mitochondrial tyrosyl-tRNA synthetase in complex with an adenylate analog

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tyrosyl-tRNA synthetase	polymer	356	39962.4	2	UniProt (Q9Y2Z4) Pfam (PF00579)	Homo sapiens (human)	Tyrosine-tRNA ligase, TyrRS
2	C, D (A, B)	5'-O-[N-(L-TYROSYL)SULFAMOYL]ADENOSINE	non-polymer		509.5	2	Chemie (YSA)
3	E, F (A, B)	water	water		18.0	90	Chemie (HOH)

Sequence modifications

A, B: 32 - 375 (UniProt: Q9Y2Z4)

PDB	External Database	Details
Met 28	-	expression tag
Arg 29	-	expression tag
Gly 30	-	expression tag
Ser 31	-	expression tag
Arg 376	-	expression tag
Ser 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79924.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1019.0
All*	Total formula weight	80943.7

*Water molecules are not included.