2PH5
Crystal structure of the homospermidine synthase hss from Legionella pneumophila in complex with NAD, Northeast Structural Genomics Target LgR54
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Homospermidine synthase | polymer | 480 | 54427.5 | 1 | UniProt (Q5ZSM2) Pfam (PF03435) Pfam (PF16653) | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 | |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 4 | D (A) | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A: 1 - 472 (UniProt: Q5ZSM2)
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | Met 1 | modified residue |
| Mse 29 | Met 29 | modified residue |
| Mse 124 | Met 124 | modified residue |
| Mse 127 | Met 127 | modified residue |
| Mse 196 | Met 196 | modified residue |
| Mse 275 | Met 275 | modified residue |
| Mse 364 | Met 364 | modified residue |
| Mse 400 | Met 400 | modified residue |
| Leu 473 | - | cloning artifact |
| Glu 474 | - | cloning artifact |
| His 475 | - | cloning artifact |
| His 476 | - | cloning artifact |
| His 477 | - | cloning artifact |
| His 478 | - | cloning artifact |
| His 479 | - | cloning artifact |
| His 480 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54427.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 759.5 | |
| All* | Total formula weight | 55186.9 |
