2PD4

Crystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan

Replaces:  1JW7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Enoyl-[acyl-carrier-protein] reductase [NADH]	polymer	275	30016.4	4	UniProt (O24990) Pfam (PF13561)	Helicobacter pylori	Enoyl-Acyl Carrier Protein Reductase, NADH- dependent enoyl-ACP reductase
2	E, G, I, K (A, B, C, D)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	4	Chemie (NAD)
3	F, H, J, L (A, B, C, D)	DICLOSAN	non-polymer		255.1	4	Chemie (DCN)
4	M, N, O, P (A, B, C, D)	water	water		18.0	218	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	120065.7
Non-Polymers*	Number of molecules	8
	Total formula weight	3674.1
All*	Total formula weight	123739.8

*Water molecules are not included.