2PBK
Crystal structure of KSHV protease in complex with hexapeptide phosphonate inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | KSHV protease | polymer | 228 | 25027.7 | 2 | UniProt (O36607) Pfam (PF00716) UniProt (by SIFTS) (Q2HRB6) | Human herpesvirus | |
| 2 | C, D (C, D) | hexapeptide phosphonate inhibitor | polymer | 7 | 751.8 | 2 | BIRD (PRD_000347) | ||
| 3 | E, F, G (A, B) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 530 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 230 (UniProt: O36607)
| PDB | External Database | Details |
|---|---|---|
| Gly 204 | Ser 204 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 51558.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 177.1 | |
| All* | Total formula weight | 51736.1 |
