2PAR
Crystal structure of the 5'-deoxynucleotidase YfbR mutant E72A complexed with Co(2+) and TMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 5'-deoxynucleotidase YfbR | polymer | 201 | 22874.2 | 2 | UniProt (P76491) Pfam (PF01966) | Escherichia coli | Nucleoside 5'-monophosphate phosphohydrolase, 5'-deoxyribonucleotidase |
| 2 | C, F (A, B) | COBALT (II) ION | non-polymer | 58.9 | 2 | Chemie (CO) PubChem (104729) | |||
| 3 | D, G (A, B) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 2 | Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (444919) PubChem (9700) PubChem (5274091) PubChem (5748250) PubChem (10147784) PubChem (129069890) PubChem (133126478) PubChem (164603144) | |||
| 4 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 199 (UniProt: P76491)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 72 | Glu 72 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45748.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 868.4 | |
| All* | Total formula weight | 46616.8 |
