2P4R
Structural basis for a novel interaction between AIP4 and beta-PIX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rho guanine nucleotide exchange factor 7 | polymer | 59 | 6731.3 | 1 | UniProt (O55043) Pfam (PF07653) | Rattus norvegicus (Norway rat) | PAK-interacting exchange factor beta, Beta-Pix |
| 2 | B (T) | E3 ubiquitin-protein ligase Itchy homolog | polymer | 25 | 2698.1 | 1 | UniProt (Q96J02) | Itch, Atrophin-1-interacting protein 4, AIP4, NFE2-associated polypeptide 1, NAPP1 | |
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F (A, T) | water | water | 18.0 | 69 | Chemie (HOH) |
Sequence modifications
A: 10 - 63 (UniProt: O55043)
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | cloning artifact |
| Pro 6 | - | cloning artifact |
| Leu 7 | - | cloning artifact |
| Gly 8 | - | cloning artifact |
| Ser 9 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 9429.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 188.2 | |
| All* | Total formula weight | 9617.6 |
