2P3T
Crystal structure of human factor XA complexed with 3-Chloro-4-(2-methylamino-imidazol-1-ylmethyl)-thiophene-2-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-6-methoxy-phenyl]-amide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor X | polymer | 52 | 5589.2 | 1 | UniProt (P00742) Pfam (PF14670) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 2 | B (B) | Coagulation factor X | polymer | 233 | 26346.0 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 3 | C (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (B) | 3-CHLORO-4-(2-METHYLAMINO-IMIDAZOL-1-YLMETHYL)-THIOPHENE-2-CARBOXYLIC ACID [4-CHLORO-2-(5-CHLORO-PYRIDIN-2-YLCARBAMOYL)-6-METHOXY-PHENYL]-AMIDE | non-polymer | 565.9 | 1 | Chemie (993) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31935.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 641.4 | |
| All* | Total formula weight | 32576.6 |
