2P1U
Crystal structure of the ligand binding domain of the retinoid X receptor alpha in complex with 3-(2'-ethoxy)-tetrahydronaphtyl cinnamic acid and a fragment of the coactivator TIF-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Retinoic acid receptor RXR-alpha | polymer | 240 | 26856.0 | 1 | UniProt (P19793) Pfam (PF00104) In PDB | Homo sapiens (human) | Retinoid X receptor alpha |
| 2 | B | Nuclear receptor coactivator 2 peptide | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) In PDB | NCoA-2, Transcriptional intermediary factor 2 | |
| 3 | A | (2E)-3-[3-(3-ETHOXY-5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)-4-HYDROXYPHENYL]ACRYLIC ACID | non-polymer | 394.5 | 1 | Chemie (4TN) | |||
| 4 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28435.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 394.5 | |
| All* | Total formula weight | 28830.4 |
