2P1D
Crystal structure of dengue methyltransferase in complex with GTP and S-Adenosyl-L-homocysteine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | type II methyltransferase | polymer | 305 | 34397.0 | 1 | UniProt (Q9WLZ8) UniProt (by SIFTS) (P12823) | Dengue virus 2 | |
| 2 | B, C, D, E, F... (A) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 3 | L (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | M (A) | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 1 | Chemie (5GP) | |||
| 5 | N (A) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 4 - 296 (UniProt: Q9WLZ8)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | expression tag |
| Arg -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Leu 70 | Met 2561 | SEE REMARK 999 |
| Arg 139 | Lys 2630 | SEE REMARK 999 |
| Ser 173 | Asn 2664 | SEE REMARK 999 |
| Val 180 | Ile 2671 | SEE REMARK 999 |
| Ser 188 | Pro 2679 | SEE REMARK 999 |
| His 201 | Tyr 2692 | SEE REMARK 999 |
| Thr 271 | Ile 2762 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34397.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1708.3 | |
| All* | Total formula weight | 36105.3 |
