2P1D
Crystal structure of dengue methyltransferase in complex with GTP and S-Adenosyl-L-homocysteine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | type II methyltransferase | polymer | 305 | 34397.0 | 1 | UniProt (Q9WLZ8) Pfam (PF01728) UniProt (by SIFTS) (P12823) In PDB | Dengue virus 2 | |
2 | A | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
3 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
4 | A | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 1 | Chemie (5GP) | |||
5 | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 4 - 296 (UniProt: Q9WLZ8)
PDB | External Database | Details |
---|---|---|
Met -8 | - | expression tag |
Arg -7 | - | expression tag |
Gly -6 | - | expression tag |
Ser -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
Gly 2 | - | expression tag |
Ser 3 | - | expression tag |
Leu 70 | Met 2561 | SEE REMARK 999 |
Arg 139 | Lys 2630 | SEE REMARK 999 |
Ser 173 | Asn 2664 | SEE REMARK 999 |
Val 180 | Ile 2671 | SEE REMARK 999 |
Ser 188 | Pro 2679 | SEE REMARK 999 |
His 201 | Tyr 2692 | SEE REMARK 999 |
Thr 271 | Ile 2762 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34397.0 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1708.3 | |
All* | Total formula weight | 36105.3 |