2P02

Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2

Replaces:  2HJ2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	S-adenosylmethionine synthetase isoform type-2	polymer	396	43807.7	1	UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773)	Homo sapiens (human)	Methionine adenosyltransferase 2, AdoMet synthetase 2, Methionine adenosyltransferase II, MAT-II
2	B (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL) PubChem (312)
3	C (A)	S-ADENOSYLMETHIONINE	non-polymer		398.4	1	Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (58766358) PubChem (73897310) PubChem (9865603) PubChem (87224684) PubChem (12312798) PubChem (131697735) PubChem (145712080) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094)
4	D (A)	water	water		18.0	512	Chemie (HOH)

Sequence modifications

A: 23 - 417 (UniProt: P31153)

PDB	External Database	Details
Ser 22	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43807.7
Non-Polymers*	Number of molecules	2
	Total formula weight	433.9
All*	Total formula weight	44241.6

*Water molecules are not included.