2OZ2
Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Cruzipain | polymer | 215 | 22715.1 | 2 | UniProt (P25779) Pfam (PF00112) | Trypanosoma cruzi | Major cysteine proteinase, Cruzaine |
| 2 | C, D, E, G, H... (A, C) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | F, L (A, C) | NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-{(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}-L-PHENYLALANINAMIDE | non-polymer | 576.7 | 2 | Chemie (D1R) | |||
| 4 | M, N (A, C) | water | water | 18.0 | 261 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45430.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1922.0 | |
| All* | Total formula weight | 47352.3 |
