2OYI

Crystal Structure of Fragment D of gammaD298,301A Fibrinogen with the Peptide Ligand Gly-Pro-Arg-Pro-Amide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Fibrinogen alpha chain	polymer	66	7747.0	2	UniProt (P02671) Pfam (PF08702) In PDB	Homo sapiens (human)
2	B, E	Fibrinogen beta chain	polymer	313	35940.2	2	UniProt (P02675) Pfam (PF08702) Pfam (PF00147) In PDB	Homo sapiens (human)
3	C, F	Fibrinogen gamma chain	polymer	311	35130.0	2	UniProt (P02679) Pfam (PF08702) Pfam (PF00147) In PDB	Homo sapiens (human)
4	G, H, I, J	GPRP Peptide	polymer	4	426.5	4
5	K, L	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	2	In PDB GlyTouCan (G21290RB)
6	B, C, E, F	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
7		water	water		18.0	150	Chemie (HOH)

Sequence modifications

C, F: 96 - 406 (UniProt: P02679)

PDB	External Database	Details
Ala 298	Asp 324	engineered mutation
Ala 301	Asp 327	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	159340.4
Branched	Number of molecules	2
	Total formula weight	1141.1
Non-Polymers*	Number of molecules	4
	Total formula weight	160.3
All*	Total formula weight	160641.8

*Water molecules are not included.