2OXM
Crystal structure of a UNG2/modified DNA complex that represent a stabilized short-lived extrahelical state in ezymatic DNA base flipping
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | DNA (5'-D(*TP*GP*TP*TP*AP*TP*CP*TP*T)-3') | polymer | 9 | 2711.8 | 1 | UDG | ||
| 2 | B (C) | DNA (5'-D(*AP*AP*AP*GP*AP*TP*(4MF)P*AP*CP*A)-3') | polymer | 10 | 3066.1 | 1 | |||
| 3 | C (A) | Uracil-DNA glycosylase | polymer | 223 | 25544.1 | 1 | UniProt (P13051) Pfam (PF03167) | Homo sapiens (human) | |
| 4 | D, E, F (B, C, A) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A: 85 - 304 (UniProt: P13051)
| PDB | External Database | Details |
|---|---|---|
| Met 82 | - | expression tag |
| Glu 83 | - | expression tag |
| Phe 84 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 31322.0 | |
| All* | Total formula weight | 31322.0 |
