2OWQ
Crystal structure of vaccinia virus uracil-DNA glycosylase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uracil-DNA glycosylase | polymer | 238 | 27253.1 | 2 | UniProt (Q91UM2) UniProt (by SIFTS) (P04303) | Vaccinia virus Western Reserve | UDG |
| 2 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 3 | D, E, H (A, B) | IMIDAZOLE | non-polymer | 69.1 | 3 | Chemie (IMD) | |||
| 4 | F, I, J, K (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | G (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | L, M (A, B) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 218 (UniProt: Q91UM2)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | cloning artifact |
| Ser -17 | - | cloning artifact |
| Ser -16 | - | cloning artifact |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | cloning artifact |
| Ser -8 | - | cloning artifact |
| Gly -7 | - | cloning artifact |
| Leu -6 | - | cloning artifact |
| Val -5 | - | cloning artifact |
| Pro -4 | - | cloning artifact |
| Arg -3 | - | cloning artifact |
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
| Asn 17 | Asp 17 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54506.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 707.1 | |
| All* | Total formula weight | 55213.4 |
