2OW6

Golgi alpha-mannosidase II complex with (1r,5s,6s,7r,8s)-1-thioniabicyclo[4.3.0]nonan-5,7,8-triol chloride

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Alpha-mannosidase 2	polymer	1045	119701.6	1	UniProt (Q24451) Pfam (PF01074) Pfam (PF09261) Pfam (PF21260) Pfam (PF07748) Pfam (PF18230) In PDB	Drosophila melanogaster (fruit fly)	Alpha-mannosidase II, Mannosyl- oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha- mannosidase II, AMAN II
2	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3	A	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	A	(1R,5S,6S,7R,8S)-1-THIONIABICYCLO[4.3.0]NONAN-5,7,8-TRIOL	non-polymer		191.3	1	Chemie (NK1)
6	A	(4R)-2-METHYLPENTANE-2,4-DIOL	non-polymer		118.2	1	Chemie (MRD)
7		water	water		18.0	1462	Chemie (HOH)

Sequence modifications

A: 13 - 1045 (UniProt: Q24451)

PDB	External Database	Details
Arg 1	-	expression tag
Ser 2	-	expression tag
Ser 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
Gly 10	-	expression tag
Glu 11	-	expression tag
Phe 12	-	expression tag
Lys 907	Glu 970	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	119701.6
Non-Polymers*	Number of molecules	6
	Total formula weight	786.0
All*	Total formula weight	120487.6

*Water molecules are not included.