2OTJ

13-deoxytedanolide bound to the large subunit of Haloarcula marismortui

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	0	23S ribosomal RNA	polymer	2922	946090.4	1	GenBank (3377779)	Haloarcula marismortui
2	9	5S ribosomal RNA	polymer	122	39318.4	1	GenBank (3377779)	Haloarcula marismortui
3	A	50S ribosomal protein L2P	polymer	240	25354.7	1	UniProt (P20276) Pfam (PF00181) Pfam (PF03947) In PDB	Haloarcula marismortui	Hmal2, Hl4
4	B	50S ribosomal protein L3P	polymer	338	37396.4	1	UniProt (P20279) Pfam (PF00297) In PDB	Haloarcula marismortui	Hmal3, Hl1
5	C	50S ribosomal protein L4P	polymer	246	26442.1	1	UniProt (P12735) Pfam (PF00573) In PDB	Haloarcula marismortui	Hmal4, Hl6
6	D	50S ribosomal protein L5P	polymer	177	19551.7	1	UniProt (P14124) Pfam (PF00281) Pfam (PF00673) In PDB	Haloarcula marismortui	Hmal5, Hl13
7	E	50S ribosomal protein L6P	polymer	178	19961.7	1	UniProt (P14135) Pfam (PF00347) In PDB	Haloarcula marismortui	Hmal6, Hl10
8	F	50S ribosomal protein L7Ae	polymer	120	12791.9	1	UniProt (P12743) Pfam (PF01248) In PDB	Haloarcula marismortui	Hs6
9	G	50S ribosomal protein L10E	polymer	348	37213.8	1	UniProt (P15825) Pfam (PF00466) Pfam (PF17777) In PDB	Haloarcula marismortui	Ribosomal protein L10, Acidic ribosomal protein P0 homolog, L10E, HMal10
10	H	50S ribosomal protein L10e	polymer	171	19068.6	1	UniProt (P60617) Pfam (PF00252) In PDB	Haloarcula marismortui
11	J	50S ribosomal protein L13P	polymer	145	16249.2	1	UniProt (P29198) Pfam (PF00572) In PDB	Haloarcula marismortui	Hmal13
12	K	50S ribosomal protein L14P	polymer	132	14191.2	1	UniProt (P22450) Pfam (PF00238) In PDB	Haloarcula marismortui	Hmal14, Hl27
13	L	50S ribosomal protein L15P	polymer	165	18005.4	1	UniProt (P12737) Pfam (PF00828) In PDB	Haloarcula marismortui	Hmal15, Hl9
14	M	50S ribosomal protein L15e	polymer	194	22157.9	1	UniProt (P60618) Pfam (PF00827) In PDB	Haloarcula marismortui	50S ribosomal protein LC12
15	N	50S ribosomal protein L18P	polymer	187	20640.9	1	UniProt (P14123) Pfam (PF17144) In PDB	Haloarcula marismortui	Hmal18, Hl12
16	O	50S ribosomal protein L18e	polymer	116	12438.9	1	UniProt (P12733) Pfam (PF00828) In PDB	Haloarcula marismortui	Hl29, L19
17	P	50S ribosomal protein L19e	polymer	149	16796.5	1	UniProt (P14119) Pfam (PF01280) In PDB	Haloarcula marismortui	Hmal19, Hl24
18	Q	50S ribosomal protein L21e	polymer	96	10567.8	1	UniProt (P12734) Pfam (PF01157) In PDB	Haloarcula marismortui	Hl31
19	R	50S ribosomal protein L22P	polymer	155	16966.9	1	UniProt (P10970) Pfam (PF00237) In PDB	Haloarcula marismortui	Hmal22, Hl23
20	S	50S ribosomal protein L23P	polymer	85	9612.5	1	UniProt (P12732) Pfam (PF00276) In PDB	Haloarcula marismortui	Hmal23, Hl25, L21
21	T	50S ribosomal protein L24P	polymer	120	13671.0	1	UniProt (P10972) Pfam (PF16906) Pfam (PF00467) In PDB	Haloarcula marismortui	Hmal24, Hl16, Hl15
22	U	50S ribosomal protein L24e	polymer	66	7233.7	1	UniProt (P14116) Pfam (PF01246) In PDB	Haloarcula marismortui	Hl21/Hl22
23	V	50S ribosomal protein L29P	polymer	71	7889.9	1	UniProt (P10971) Pfam (PF00831) In PDB	Haloarcula marismortui	Hmal29, Hl33
24	W	50S ribosomal protein L30P	polymer	154	17062.9	1	UniProt (P14121) Pfam (PF00327) In PDB	Haloarcula marismortui	Hmal30, Hl20, Hl16
25	X	50S ribosomal protein L31e	polymer	92	10384.6	1	UniProt (P18138) Pfam (PF01198) In PDB	Haloarcula marismortui	L34, Hl30
26	Y	50S ribosomal protein L32e	polymer	241	26455.7	1	UniProt (P12736) Pfam (PF14520) Pfam (PF01655) In PDB	Haloarcula marismortui	Hl5
27	Z	50S ribosomal protein L37Ae	polymer	73	8294.2	1	UniProt (P60619) Pfam (PF01780) In PDB	Haloarcula marismortui
28	1	50S ribosomal protein L37e	polymer	57	6330.2	1	UniProt (P32410) Pfam (PF01907) In PDB	Haloarcula marismortui	L35e
29	2	50S ribosomal protein L39e	polymer	50	6133.1	1	UniProt (P22452) Pfam (PF00832) In PDB	Haloarcula marismortui	Hl39e, Hl46e
30	3	50S ribosomal protein L44E	polymer	92	10815.2	1	UniProt (P32411) Pfam (PF00935) In PDB	Haloarcula marismortui	La, Hla
31	I	50S ribosomal protein L11P	polymer	161	16966.4	1	UniProt (P14122) Pfam (PF03946) Pfam (PF00298) In PDB	Haloarcula marismortui	Hmal11
32	0	13-DEOXYTEDANOLIDE	non-polymer		594.7	1	Chemie (13T)
33	0, 3, K, 9, T...	MAGNESIUM ION	non-polymer		24.3	117	Chemie (MG)
34	0	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
35	0, C, H, J, L...	SODIUM ION	non-polymer		23.0	86	Chemie (NA)
36	J, 3, 0, L, M...	CHLORIDE ION	non-polymer		35.5	22	Chemie (CL)
37	3, O, U, Z, 1	CADMIUM ION	non-polymer		112.4	5	Chemie (CD)
38		water	water		18.0	7784	Chemie (HOH)

Sequence modifications

0: 2 - 2923 (GenBank: 3377779)

PDB	External Database	Details
C 560	U 3155	conflict
1ma 628	A 3223	modified residue
Omu 2587	U 5182	modified residue
Omg 2588	G 5183	modified residue
Ur3 2619	U 5214	modified residue
Psu 2621	U 5216	modified residue

C: 1 - 246 (UniProt: P12735)

PDB	External Database	Details
Leu 73	Gln 73	conflict

G: 1 - 348 (UniProt: P15825)

PDB	External Database	Details
Asp 248	Ala 248	conflict

H: 1 - 163 (UniProt: P60617)

PDB	External Database	Details
Asp 164	-	insertion
Ser 165	-	insertion
Ser 166	-	insertion
Pro 167	-	insertion
Ala 168	-	insertion
Gly 169	-	insertion
Asn 170	-	insertion
Ala 171	-	insertion

K: 1 - 132 (UniProt: P22450)

PDB	External Database	Details
Leu 44	His 44	conflict

M: 1 - 193 (UniProt: P60618)

PDB	External Database	Details
Glu 13	Lys 14	conflict
Ala 194	-	insertion

Z: 11 - 82 (UniProt: P60619)

PDB	External Database	Details
Arg 10	-	insertion

Contents of the asymmetric unit

Polymers	Number of chains	31
	Total formula weight	1472054.0
Non-Polymers*	Number of molecules	233
	Total formula weight	6835.8
All*	Total formula weight	1478889.7

*Water molecules are not included.