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2OS6

Solution structure of LARG PDZ domain in complex with C-terminal octa-peptide of Plexin B1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Rho guanine nucleotide exchange factor 12polymer899369.71UniProt (Q9NZN5)
Pfam (PF00595)
Homo sapiens (human)LARG protein, Leukemia-associated RhoGEF
2B
(B)
C-terminal peptide of Plexin-B1polymer8918.01UniProt (O43157)Semaphorin receptor SEP
Sequence modifications
A: 5 - 89 (UniProt: Q9NZN5)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
His 3-expression tag
Met 4-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight10287.7
All*Total formula weight10287.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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