2OOH
Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Macrophage migration inhibitory factor | polymer | 114 | 12355.1 | 3 | UniProt (P14174) Pfam (PF01187) | Homo sapiens (human) | MIF, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, (EC 5.3.2.1) |
| 2 | D, E, F, G, H... (A, B, C) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | K, M (B, C) | 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME | non-polymer | 247.3 | 2 | Chemie (OX3) | |||
| 4 | N, O (C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | P, Q, R (A, B, C) | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37065.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1447.3 | |
| All* | Total formula weight | 38512.4 |
