2ONI
Catalytic Domain of the Human NEDD4-like E3 Ligase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase NEDD4-like protein | polymer | 392 | 47247.5 | 1 | UniProt (Q96PU5) Pfam (PF00632) | Homo sapiens (human) | Nedd4-2, NEDD4.2, NEDD4-like ubiquitin-protein ligase, neural precursor cell expressed, developmentally down-regulated 4-like, ubiquitin-protein ligase NEDD4-like, developmentally down-regulated gene 4-like, ubiquitin-protein ligase Rsp5 |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | C (A) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
A: 574 - 947 (UniProt: Q96PU5)
| PDB | External Database | Details |
|---|---|---|
| Mse 556 | - | cloning artifact |
| His 557 | - | cloning artifact |
| His 558 | - | cloning artifact |
| His 559 | - | cloning artifact |
| His 560 | - | cloning artifact |
| His 561 | - | cloning artifact |
| His 562 | - | cloning artifact |
| Ser 563 | - | cloning artifact |
| Ser 564 | - | cloning artifact |
| Gly 565 | - | cloning artifact |
| Arg 566 | - | cloning artifact |
| Glu 567 | - | cloning artifact |
| Asn 568 | - | cloning artifact |
| Leu 569 | - | cloning artifact |
| Tyr 570 | - | cloning artifact |
| Phe 571 | - | cloning artifact |
| Gln 572 | - | cloning artifact |
| Gly 573 | - | cloning artifact |
| Mse 600 | Met 620 | modified residue |
| Mse 616 | Met 636 | modified residue |
| Mse 655 | Met 675 | modified residue |
| Mse 718 | Met 738 | modified residue |
| Mse 719 | Met 739 | modified residue |
| Mse 729 | Met 749 | modified residue |
| Mse 754 | Met 774 | modified residue |
| Mse 778 | Met 798 | modified residue |
| Mse 804 | Met 824 | modified residue |
| Mse 832 | Met 852 | modified residue |
| Mse 870 | Met 890 | modified residue |
| Mse 890 | Met 910 | modified residue |
| Mse 943 | Met 963 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47247.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 47270.5 |
