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2OJF

Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine based inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
cAMP-dependent protein kinase, alpha-catalytic subunitpolymer35140677.71UniProt (P00517)
Pfam (PF00069)
Bos taurus (cattle)PKA C-alpha
2B
(I)
Inhibitory peptidepolymer202226.41
3C
(E)
(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINEnon-polymer384.41Chemie (4PY)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42904.1
Non-Polymers*Number of molecules1
Total formula weight384.4
All*Total formula weight43288.5
*Water molecules are not included.

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PDB entries from 2024-11-06

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