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2OH0

Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine Based Inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1EcAMP-dependent protein kinase, alpha-catalytic subunitpolymer35140677.71UniProt (P00517)
Pfam (PF00069)
In PDB
Bos taurus (cattle)PKA C-alpha
2IInhibitory peptidepolymer202226.41
3E(2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINEnon-polymer383.41Chemie (2PY)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42904.1
Non-Polymers*Number of molecules1
Total formula weight383.4
All*Total formula weight43287.5
*Water molecules are not included.

222926

PDB entries from 2024-07-24

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