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2OH0

Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine Based Inhibitors

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
cAMP-dependent protein kinase, alpha-catalytic subunitpolymer35140677.71UniProt (P00517)
Pfam (PF00069)
Bos taurus (cattle)PKA C-alpha
2B
(I)
Inhibitory peptidepolymer202226.41
3C
(E)
(2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINEnon-polymer383.41Chemie (2PY)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42904.1
Non-Polymers*Number of molecules1
Total formula weight383.4
All*Total formula weight43287.5
*Water molecules are not included.

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PDB entries from 2025-12-10

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