2OH0
Crystal structure of Protein Kinase A in complex with Pyridine-Pyrazolopyridine Based Inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E | cAMP-dependent protein kinase, alpha-catalytic subunit | polymer | 351 | 40677.7 | 1 | UniProt (P00517) Pfam (PF00069) In PDB | Bos taurus (cattle) | PKA C-alpha |
2 | I | Inhibitory peptide | polymer | 20 | 2226.4 | 1 | |||
3 | E | (2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINE | non-polymer | 383.4 | 1 | Chemie (2PY) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42904.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 383.4 | |
All* | Total formula weight | 43287.5 |