2OFX
crystal structure of the APSK domain of human PAPSS1 in complex with ADPMg and PAPS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 | polymer | 207 | 22928.9 | 2 | UniProt (O43252) Pfam (PF01583) | Homo sapiens (human) | |
| 2 | C, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D, E, I, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 4 | F, K (A, B) | 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE | non-polymer | 507.3 | 2 | Chemie (PPS) | |||
| 5 | G, L (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 227 (UniProt: O43252)
| PDB | External Database | Details |
|---|---|---|
| Gln 21 | - | cloning artifact |
| Gly 22 | - | cloning artifact |
| His 23 | - | cloning artifact |
| - | Glu 2 | deletion |
| - | Ile 3 | deletion |
| - | Pro 4 | deletion |
| - | Gly 5 | deletion |
| - | Ser 6 | deletion |
| - | Leu 7 | deletion |
| - | Cys 8 | deletion |
| - | Lys 9 | deletion |
| - | Lys 10 | deletion |
| - | Val 11 | deletion |
| - | Lys 12 | deletion |
| - | Leu 13 | deletion |
| - | Ser 14 | deletion |
| - | Asn 15 | deletion |
| - | Asn 16 | deletion |
| - | Ala 17 | deletion |
| - | Gln 18 | deletion |
| - | Asn 19 | deletion |
| - | Trp 20 | deletion |
| - | Gly 21 | deletion |
| - | Met 22 | deletion |
| - | Gln 23 | deletion |
| - | Arg 24 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45857.7 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2297.4 | |
| All* | Total formula weight | 48155.1 |
