2OFW
Crystal structure of the APSK domain of human PAPSS1 complexed with 2 APS molecules
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | APS kinase domain of the PAPS synthetase 1 | polymer | 208 | 23100.1 | 8 | UniProt (O43252) Pfam (PF01583) | Homo sapiens (human) | |
| 2 | AA, CA, DA, I, J... (G, H, A, B, C...) | ADENOSINE-5'-PHOSPHOSULFATE | non-polymer | 427.3 | 16 | Chemie (ADX) | |||
| 3 | BA, K, N, Q, T... (H, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 4 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 832 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 20 - 227 (UniProt: O43252)
| PDB | External Database | Details |
|---|---|---|
| Gln 20 | - | cloning artifact |
| Gly 21 | - | cloning artifact |
| His 22 | - | cloning artifact |
| - | Glu 2 | deletion |
| - | Ile 3 | deletion |
| - | Pro 4 | deletion |
| - | Gly 5 | deletion |
| - | Ser 6 | deletion |
| - | Leu 7 | deletion |
| - | Cys 8 | deletion |
| - | Lys 9 | deletion |
| - | Lys 10 | deletion |
| - | Val 11 | deletion |
| - | Lys 12 | deletion |
| - | Leu 13 | deletion |
| - | Ser 14 | deletion |
| - | Asn 15 | deletion |
| - | Asn 16 | deletion |
| - | Ala 17 | deletion |
| - | Gln 18 | deletion |
| - | Asn 19 | deletion |
| - | Trp 20 | deletion |
| - | Gly 21 | deletion |
| - | Met 22 | deletion |
| - | Gln 23 | deletion |
| Ile 55 | Val 55 | conflict |
| Asn 221 | Gln 221 | conflict |
| Leu 226 | Val 226 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 184800.7 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 6982.4 | |
| All* | Total formula weight | 191783.0 |
