2OCV
Structural basis of Na+ activation mimicry in murine thrombin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thrombin | polymer | 42 | 4820.4 | 1 | UniProt (P19221) Pfam (PF09396) | Mus musculus (house mouse) | |
| 2 | B (B) | Thrombin | polymer | 259 | 30011.6 | 1 | UniProt (P19221) Pfam (PF00089) | Mus musculus (house mouse) | |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E, F, G (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
B: 16 - 246 (UniProt: P19221)
| PDB | External Database | Details |
|---|---|---|
| Ala 236 | Arg 608 | conflict |
| Glu 247 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34832.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 36141.3 |
