2OCK
Crystal structure of valacyclovir hydrolase D123N mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Valacyclovir hydrolase | polymer | 254 | 28870.1 | 1 | UniProt (Q86WA6) Pfam (PF00561) In PDB | Homo sapiens (human) | VACVase, Biphenyl hydrolase-like protein, Biphenyl hydrolase-related protein, Bph-rp, Breast epithelial mucin-associated antigen, MCNAA |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence modifications
A: 21 - 274 (UniProt: Q86WA6)
| PDB | External Database | Details |
|---|---|---|
| Asn 123 | Asp 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28870.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 79.2 | |
| All* | Total formula weight | 28949.3 |
