2O8Y

Apo IRAK4 Kinase Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Interleukin-1 receptor-associated kinase 4	polymer	298	33997.0	2	UniProt (Q9NWZ3) Pfam (PF07714)	Homo sapiens (human)	IRAK-4, NY- REN-64 antigen
2	C, D (A, B)	water	water		18.0	59	Chemie (HOH)

Sequence modifications

A, B: 163 - 460 (UniProt: Q9NWZ3)

PDB	External Database	Details
Mse 192	Met 192	modified residue
Mse 237	Met 237	modified residue
Mse 265	Met 265	modified residue
Mse 287	Met 287	modified residue
Tpo 342	Thr 342	modified residue
Mse 344	Met 344	modified residue
Tpo 345	Thr 345	modified residue
Mse 355	Met 355	modified residue
Mse 418	Met 418	modified residue
Mse 429	Met 429	modified residue
Mse 457	Met 457	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67993.9
All*	Total formula weight	67993.9

*Water molecules are not included.