2O7N
CD11A (LFA1) I-domain complexed with 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Integrin alpha-L | polymer | 183 | 20936.0 | 1 | UniProt (P20701) Pfam (PF00092) In PDB | Homo sapiens (human) | Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, Leukocyte function-associated molecule 1 alpha chain, CD11a antigen |
| 2 | A | 7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile | non-polymer | 408.3 | 1 | Chemie (2O7) | |||
| 3 | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 129 - 307 (UniProt: P20701)
| PDB | External Database | Details |
|---|---|---|
| Gly 125 | - | cloning artifact |
| Ser 126 | - | cloning artifact |
| His 127 | - | cloning artifact |
| Met 128 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20936.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 408.3 | |
| All* | Total formula weight | 21344.3 |
