2O7M
The C-terminal loop of the homing endonuclease I-CreI is essential for DNA binding and cleavage. Identification of a novel site for specificity engineering in the I-CreI scaffold
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DNA endonuclease I-CreI | polymer | 156 | 17934.6 | 2 | UniProt (P05725) Pfam (PF00961) In PDB | Chlamydomonas reinhardtii | LAGLIDAG HOMING ENDONUCLEASE, 23S rRNA intron protein |
2 | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 156 (UniProt: P05725)
PDB | External Database | Details |
---|---|---|
Thr 42 | Ala 42 | conflict |
Glu 110 | Trp 110 | conflict |
Gln 111 | Arg 111 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 35869.3 | |
All* | Total formula weight | 35869.3 |