2O65
Crystal structure of Pim1 with Pentahydroxyflavone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Proto-oncogene serine/threonine-protein kinase Pim-1 | polymer | 293 | 33832.3 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (human) | |
| 2 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 3 | A | 5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE | non-polymer | 302.2 | 1 | Chemie (MYF) | |||
| 4 | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence modifications
A: 29 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Val 314 | - | cloning artifact |
| Asp 315 | - | cloning artifact |
| His 316 | - | cloning artifact |
| His 317 | - | cloning artifact |
| His 318 | - | cloning artifact |
| His 319 | - | cloning artifact |
| His 320 | - | cloning artifact |
| His 321 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33832.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 371.3 | |
| All* | Total formula weight | 34203.6 |
