2O4K
Crystal Structure of HIV-1 Protease (Q7K) in Complex with Atazanavir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | protease | polymer | 99 | 10804.8 | 2 | UniProt (P03367) Pfam (PF00077) UniProt (by SIFTS) (Q903J0) | Human immunodeficiency virus 1 | |
| 2 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 3 | D (A) | (3S,8S,9S,12S)-3,12-BIS(1,1-DIMETHYLETHYL)-8-HYDROXY-4,11-DIOXO-9-(PHENYLMETHYL)-6-[[4-(2-PYRIDINYL)PHENYL]METHYL]-2,5, 6,10,13-PENTAAZATETRADECANEDIOIC ACID DIMETHYL ESTER | non-polymer | 704.9 | 1 | Chemie (DR7) PubChem (148192) PubChem (21696352) PubChem (22940470) PubChem (44182297) PubChem (22940469) PubChem (53667683) PubChem (56971648) PubChem (59651325) PubChem (60098916) PubChem (71306984) PubChem (92402749) PubChem (93971971) PubChem (93971973) PubChem (6101863) PubChem (6540550) PubChem (6540690) PubChem (9962872) PubChem (131839569) PubChem (134694218) PubChem (66587081) PubChem (71313511) PubChem (90944682) PubChem (93971972) PubChem (99650408) PubChem (124636677) PubChem (138393803) PubChem (138393804) PubChem (144108234) PubChem (144517104) PubChem (173493799) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 506 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21609.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 740.3 | |
| All* | Total formula weight | 22349.9 |
