2O3Z
X-ray crystal structure of LpxC complexed with 3-heptyloxybenzoate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase | polymer | 271 | 30989.5 | 2 | UniProt (O67648) Pfam (PF03331) | Aquifex aeolicus | UDP-3-O-acyl-GlcNAc deacetylase |
| 2 | C, H (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D, E, I, J, K (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 4 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G, L (A, B) | 3-(heptyloxy)benzoic acid | non-polymer | 236.3 | 2 | Chemie (AI7) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 283 (UniProt: O67648)
| PDB | External Database | Details |
|---|---|---|
| Ala 193 | Cys 181 | engineered mutation |
| - | Asp 272 | deletion |
| - | Leu 273 | deletion |
| - | Pro 274 | deletion |
| - | His 275 | deletion |
| - | Leu 276 | deletion |
| - | Pro 277 | deletion |
| - | Ser 278 | deletion |
| - | Val 279 | deletion |
| - | Gln 280 | deletion |
| - | Ala 281 | deletion |
| - | Leu 282 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61979.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1027.2 | |
| All* | Total formula weight | 63006.3 |
