2O3H
Crystal structure of the human C65A Ape
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-(apurinic or apyrimidinic site) lyase | polymer | 285 | 32011.4 | 1 | UniProt (P27695) Pfam (PF03372) | Homo sapiens (human) | AP endonuclease 1, APEX nuclease, APEN, REF-1 protein, Apurinic/apyrimidinic endonuclease |
| 2 | B, C (A) | SAMARIUM (III) ION | non-polymer | 150.4 | 2 | Chemie (SM) | |||
| 3 | D, E, F, G (A) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | H (A) | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A: 40 - 318 (UniProt: P27695)
| PDB | External Database | Details |
|---|---|---|
| Gly 34 | - | expression tag |
| Ser 35 | - | expression tag |
| His 36 | - | expression tag |
| Met 37 | - | expression tag |
| Ala 38 | - | expression tag |
| Ser 39 | - | expression tag |
| Ala 65 | Cys 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32011.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 536.9 | |
| All* | Total formula weight | 32548.3 |
