2O3B
Crystal structure complex of Nuclease A (NucA) with intra-cellular inhibitor NuiA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclease | polymer | 241 | 26375.4 | 1 | UniProt (P38446) Pfam (PF01223) | Nostoc sp. | Endonuclease |
| 2 | B (B) | Sugar-non-specific nuclease inhibitor | polymer | 136 | 15133.8 | 1 | UniProt (Q7A260) Pfam (PF07924) | Nostoc sp. | |
| 3 | C, D (A) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 4 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | F, G (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
A: 35 - 274 (UniProt: P38446)
B: 2 - 135 (UniProt: Q7A260)
| PDB | External Database | Details |
|---|---|---|
| Gly 34 | - | cloning artifact |
| Ala 121 | Asp 121 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | cloning artifact |
| Ser 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41509.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 532.2 | |
| All* | Total formula weight | 42041.4 |
