2O2V
Crystal Structure of the Complex of Human Mitogen Activated Protein Kinase Kinase 5 Phox Domain (MAP2K5-phox) with Human Mitogen Activated Protein Kinase Kinase Kinase 3 (MAP3K3B-phox)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity mitogen-activated protein kinase kinase 5 | polymer | 106 | 11941.5 | 1 | UniProt (Q13163) Pfam (PF00564) | Homo sapiens (human) | MAP kinase kinase 5, MAPKK 5, MAPK/ERK kinase 5 |
| 2 | B (B) | Mitogen-activated protein kinase kinase kinase 3 | polymer | 90 | 10484.9 | 1 | UniProt (Q99759) Pfam (PF00564) | Homo sapiens (human) | MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3 |
| 3 | C, D (A, B) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A: 5 - 108 (UniProt: Q13163)
B: 37 - 124 (UniProt: Q99759)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | - | cloning artifact |
| Met 4 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Ser 35 | - | cloning artifact |
| Met 36 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22426.4 | |
| All* | Total formula weight | 22426.4 |
