2O23
The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HADH2 protein | polymer | 265 | 27286.3 | 2 | UniProt (Q6IBS9) Pfam (PF00106) UniProt (by SIFTS) (Q99714) | Homo sapiens (human) | Hydroxyacyl-Coenzyme A dehydrogenase, type II |
| 2 | C, D (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | E (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 614 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 261 (UniProt: Q6IBS9)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | cloning artifact |
| His 0 | - | cloning artifact |
| Gly 262 | - | cloning artifact |
| Ser 263 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54572.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1418.9 | |
| All* | Total formula weight | 55991.6 |
