2NZ4
Structural investigation of the GlmS ribozyme bound to its catalytic cofactor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | E, F, G, H | substrate strand RNA 13-mer | polymer | 13 | 4177.6 | 4 | |||
2 | P, Q, R, S | GlmS ribozyme | polymer | 141 | 45624.9 | 4 | |||
3 | A, B, C, D | U1 Small Nuclear Ribonucleoprotein A | polymer | 94 | 10941.8 | 4 | UniProt (P09012) Pfam (PF00076) In PDB | Homo sapiens (human) | U1 snRNP protein A; U1A protein; U1-A |
4 | H, P, F, G | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose | non-polymer | 259.2 | 4 | Chemie (GLP) | |||
5 | R, H, S, P, F... | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) | |||
6 | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 5 - 98 (UniProt: P09012)
PDB | External Database | Details |
---|---|---|
His 31 | Tyr 30 | engineered mutation |
Arg 36 | Gln 35 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 242977.1 | |
Non-Polymers* | Number of molecules | 20 |
Total formula weight | 1425.5 | |
All* | Total formula weight | 244402.5 |