2NZ4
Structural investigation of the GlmS ribozyme bound to its catalytic cofactor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (E, F, G, H) | substrate strand RNA 13-mer | polymer | 13 | 4177.6 | 4 | |||
| 2 | B, D, F, H (P, Q, R, S) | GlmS ribozyme | polymer | 141 | 45624.9 | 4 | |||
| 3 | I, J, K, L (A, B, C, D) | U1 Small Nuclear Ribonucleoprotein A | polymer | 94 | 10941.8 | 4 | UniProt (P09012) Pfam (PF00076) | Homo sapiens (human) | U1 snRNP protein A; U1A protein; U1-A |
| 4 | BA, M, R, W (H, P, F, G) | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose | non-polymer | 259.2 | 4 | Chemie (GLP) PubChem (609) PubChem (24961603) PubChem (44246482) PubChem (57998442) PubChem (439217) PubChem (59627972) PubChem (440997) PubChem (70946575) PubChem (70946783) PubChem (71089772) PubChem (89574559) PubChem (5460111) PubChem (92209468) PubChem (9838047) PubChem (11557954) PubChem (11637467) PubChem (16019957) PubChem (133126500) PubChem (172138827) PubChem (172641958) | |||
| 5 | AA, CA, DA, EA, FA... (R, H, S, P, F...) | MAGNESIUM ION | non-polymer | 24.3 | 16 | Chemie (MG) PubChem (888) | |||
| 6 | GA, HA, IA, JA, KA... (E, P, F, Q, G...) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 5 - 98 (UniProt: P09012)
| PDB | External Database | Details |
|---|---|---|
| His 31 | Tyr 30 | engineered mutation |
| Arg 36 | Gln 35 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 242977.1 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1425.5 | |
| All* | Total formula weight | 244402.5 |
