2NTA
Crystal Structure of PTP1B-inhibitor Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 299 | 34819.7 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (human) | Protein-tyrosine phosphatase 1B, PTP-1B |
| 2 | A | 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE | non-polymer | 328.8 | 1 | Chemie (521) | |||
| 3 | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A: 1 - 299 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Asp 252 | Glu 252 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34819.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 328.8 | |
| All* | Total formula weight | 35148.5 |
