2NT0
Acid-beta-glucosidase low pH, glycerol bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glucosylceramidase | polymer | 497 | 55640.2 | 4 | UniProt (P04062) Pfam (PF02055) Pfam (PF17189) | Homo sapiens (human) | Beta-glucocerebrosidase, Acid beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, Alglucerase, Imiglucerase |
| 2 | E, FA, L, M, W (A, D, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 3 | F, G, GA, H, HA... (A, D, B, C) | SULFATE ION | non-polymer | 96.1 | 20 | Chemie (SO4) | |||
| 4 | AA, BA, CA, DA, EA... (C, A, D, B) | GLYCEROL | non-polymer | 92.1 | 13 | Chemie (GOL) | |||
| 5 | QA, RA, SA, TA (A, B, C, D) | water | water | 18.0 | 1710 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 497 (UniProt: P04062)
| PDB | External Database | Details |
|---|---|---|
| His 495 | Arg 534 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 222560.7 | |
| Non-Polymers* | Number of molecules | 38 |
| Total formula weight | 4224.5 | |
| All* | Total formula weight | 226785.2 |
