2NQZ
Trna-guanine transglycosylase (TGT) mutant in complex with 7-deaza-7-aminomethyl-guanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Queuine tRNA-ribosyltransferase | polymer | 385 | 42748.4 | 1 | UniProt (P28720) Pfam (PF01702) | Zymomonas mobilis | TGT, tRNA-guanine transglycosylase, Guanine insertion enzyme |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 7-DEAZA-7-AMINOMETHYL-GUANINE | non-polymer | 179.2 | 1 | Chemie (PRF) | |||
| 4 | D, E, F, G, H... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | J (A) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A: 2 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Phe 106 | Tyr 105 | engineered mutation |
| Val 158 | Cys 157 | engineered mutation |
| Ser 232 | Ala 231 | engineered mutation |
| Gly 233 | Val 232 | engineered mutation |
| Lys 312 | Thr 311 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42748.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 797.2 | |
| All* | Total formula weight | 43545.6 |
